A new approach to treatment resistant depression
Spravato®: A Groundbreaking Treatment for Depression
Spravato® (esketamine) is a game-changing nasal spray for depression that has been FDA-approved to offer a new hope for those struggling with depression, especially individuals with treatment-resistant depression. If traditional antidepressants haven’t worked for you, Spravato for depression may be the solution you’ve been waiting for.
Unlike oral antidepressants, which can take weeks or even months to show noticeable effects, Spravato® nasal spray works quickly, often providing relief within hours to days. This rapid-acting treatment targets brain chemistry in a unique way, offering much-needed relief to those who have not found success with other treatments. If you’ve been battling depression and feeling stuck with medications that don’t seem to help, Spravato treatment for depression could make a significant difference.


Spravato® nasal spray for depression is particularly effective for individuals with treatment-resistant depression (TRD). TRD refers to depression that has not responded to at least two different antidepressant medications. For people experiencing TRD, Spravato treatment resistant depression is often an ongoing struggle. But with Spravato®, there’s hope for finding relief. This innovative treatment works differently from traditional medications by targeting NMDA receptors in the brain, which are thought to play a role in mood regulation.
Another benefit of Spravato® (esketamine) is its ability to complement traditional treatments. You can use it alongside your current medications, enhancing their effectiveness and helping you achieve better results. It’s a great option if you’re looking to try something new or need extra support in managing your symptoms.

Many people wonder, “Is Spravato covered by insurance?”
The answer depends on your insurance provider and specific plan. However, Spravato® is often covered by insurance, especially for those with treatment-resistant depression. At Wilshire Institute for Interventional Psychiatry we have a full Patient Advocate team dedicated to working with most commercial insurances to keep costs as low as possible for you.
If you’re considering Spravato® nasal spray for depression, it’s essential to know that it’s administered under the supervision of a healthcare provider in a certified medical office. After your treatment, you’ll remain at the clinic for observation for about two hours to ensure your safety. This ensures that the treatment is both effective and well-monitored, especially since esketamine nasal spray can cause temporary side effects such as dizziness or increased blood pressure.

However, it has proven to be an invaluable tool in helping people manage their depression symptoms and regain a sense of normalcy in their lives. For many, it has been a life-changing treatment that has allowed them to engage more effectively with other therapeutic options, like cognitive behavioral therapy for depression, and ultimately improve their overall mental well-being.
Whether you’ve struggled with depression for years or have recently been diagnosed, Spravato® nasal spray might be the breakthrough treatment you need. If you’re tired of feeling stuck with traditional medications that just don’t seem to work, it may be time to talk to your healthcare provider about Spravato for depression. With its rapid effects and potential for lasting relief, Spravato® offers a new approach to depression treatment, providing hope for many people who haven’t found success with other options.
It is typically used alongside oral antidepressants to enhance the effectiveness of your treatment plan. By combining Spravato® with your current medications, it can work more quickly and provide a more robust treatment for major depressive disorder (MDD), especially for those who have not found success with traditional antidepressants.


We understand that depression can feel overwhelming, and our team is here to help you find the treatment that works best for you. If you’re struggling with MDD and seeking treatment for depression in Beverly Hills, FDA-approved Spravato® might be just the solution you need.
Spravato® works rapidly, often providing relief within hours to days, making it a great option for those who have not experienced significant improvement with traditional treatments. Under the care of our expert providers, you’ll receive close monitoring during each session to ensure your safety and comfort throughout the process.
Whether you are looking for a new option to complement your existing treatment or you’re exploring advanced therapies for the first time, Spravato® offers a promising path to recovery. At Wilshire Institute, we’re here to guide you on your journey toward better mental health with personalized care and support every step of the way.

A challenging condition where individuals don’t experience relief from their symptoms despite trying multiple antidepressant medications or therapies. TRD can be incredibly frustrating and disheartening for patients who have put in significant effort to manage their condition, only to feel as though they’re not making progress.
At Wilshire Institute for Interventional Psychiatry, we understand how difficult it can be to face depression when nothing seems to work. We offer specialized treatments like Spravato®, which is FDA-approved for treatment-resistant depression. Spravato® works rapidly, offering a new hope for those who haven’t found relief from traditional treatments.
Whether you’re struggling with MDD or have been dealing with TRD, we’ll work with you closely to develop a treatment plan that addresses both the emotional and physical aspects of your condition. You don’t have to navigate this journey alone.
If you’re ready to regain control over your mental health, Wilshire Institute is here to help. We’ll guide you through every step of the process, ensuring you receive the care and support you need to start feeling better.

Insurance Coverage for Spravato® Treatment
At Wilshire Institute for Interventional Psychiatry, we understand that the cost of treatment is an important consideration in your healthcare journey. Our goal is to make sure you get the support you need without unnecessary stress about expenses. That’s why we’re pleased to inform you that most insurance plans cover Spravato® treatment for those who qualify. This can make accessing this groundbreaking treatment for treatment-resistant depression (TRD) more affordable and accessible.
Navigating insurance coverage can be confusing, but you don’t have to do it alone. We have a dedicated Patient Advocacy team to handle all of the logistics and paperwork for you. We’re committed to ensuring that financial concerns don’t stand in the way of your mental health care and typically your cost for treatment is a simple co-pay. Our goal is to make accessing treatment as smooth and easy as possible, so you can focus on your healing journey.

Reach out today to learn more about Spravato® treatment and discuss how we can help you get started.
An Evidence-Based Solution for Treatment-Resistant Depression
Spravato® (also known as esketamine) is an evidence-based solution offering a breakthrough treatment for treatment-resistant depression (TRD). It has similarities to ketamine, which has been FDA-approved for over 60 years as an anesthetic and has been successfully used for treating depression, anxiety, and PTSD for many years.
Doctors across the country have been using ketamine treatments to help people with TRD and related conditions, and now Spravato® gives patients a refined treatment option with quick and promising results.
At Wilshire Institute for Interventional Psychiatry, our clinical team is specially trained and experienced in providing Spravato® treatment, ensuring you receive the best care throughout your experience. We are dedicated to making sure your treatment journey is as smooth and comfortable as possible.


Additionally, our Patient Advocates are here to guide you through the entire process, helping you understand how Spravato® works, addressing any concerns you may have, and assisting with navigating the insurance and scheduling process.
If you’re in the Los Angeles area and dealing with treatment-resistant depression, give us a call. We’re here to help you find the right solution and get you started on the path to feeling better. Spravato® may be exactly what you need to take control of your mental health.

Frequently Asked Questions
These FAQs provide basic information about Spravato, but patients should always consult their healthcare provider for personalized advice and guidance regarding its use.
Spravato™ is a prescription medicine administered as a nasal spray and used along with an antidepressant, taken by mouth to treat: Adults with treatment-resistant depression (TRD) Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions.
Spravato™ is FDA approved exclusively for adults living with depression who have not responded well to other treatments. Spravato is for adults who have treatment-resistant depression. The drug may also be used to help adults who are having suicidal thoughts because of severe depressive disorder. To determine if Spravato™ is right for you, contact the team at Wilshire Institute to discuss your specific situation and treatment options.
Although Spravato™ esketamine is administered as a nasal spray, people are not permitted to purchase it for home use. Patients may receive Spravato under medical supervision at a clinic or doctor’s office that has been certified by the maker of Spravato™ as an authorized provider. Wilshire Institute is a certified authorized provider of Spravato™.
Spravato™ is not for everyone. Spravato™ is only approved for adults suffering from Treatment Resistant Depression (TRD). To determine if you qualify, your doctor will work with you on the qualification process. Contact the team at Wilshire Institute to discuss your specific situation, review the qualification requirements, and learn about treatment options.
Spravato™ is covered by most insurance. Wilshire Institute Patient Advocates will work with you and your insurance to ensure treatments are available to you as quickly as possible and with minimal out-of-pocket cost. In addition to the coverage provided by your insurance, Janssen, the maker of Spravato, offers a program to help cover much of your out-of-pocket co-share or co-pay. You will have a personal Patient Advocate assigned to you that will manage all of the insurance and related paperwork so that you can focus on your treatments and your recovery. To learn more, call us now and speak to a Patient Advocate today.
Call Wilshire Institute to learn more about Spravato™. For additional information about Spravato™ from Janssen Pharmaceuticals, Inc., the maker of Spravato™, visit www.spravato.com